CAAS: Cancer Associated annotation of Alternative Splicing

Description

The CAAS database presents a graphical overview of tissue specific alternative splicing (AS) annotation for 600 breast and ovarian cancer associated genes. To date, these genes have been annotated by comprehensive RT-PCR in two, 4-patient serous ovarian tumour pools, and 2, 4-patient normal ovary pools. The gene list was obtained by a keyword search for "ovarian cancer" or "breast cancer" on Entrez Gene (http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene), performed in December 2005, followed by selection of those genes showing evidence of alternative splicing in the Aceview database (http://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/index.html). Both the existence of all possible exon-exon junctions and the relative ratios for each AS variant from end-point RT-PCR data are presented in graphical form. Full details on the interpretation of the data can be obtained in Klinck et al., Cancer Res 68(3), 657-63, 2008

Supplementary Figures and Tables for Klinck et al., Cancer Res 68(3), 657-63, 2008

  • Supplementary Tables and Figures Legends
  • Supplementary Figure 1
  • Supplementary Figure 2
  • Supplementary Figure 3_14
  • Supplementary Figure 3_24
  • Supplementary Figure 3_34
  • Supplementary Figure 3_44
  • Supplementary Figure 4
  • Supplementary Table 1
  • Supplementary Table 2
  • Genes

    For questions or comments, contact Sherif Abou Elela.
    © 2005-2006, Sherbrooke Center for Functional Genomics.